The CoreNAT unit Biomolecular Interactions provides biophysical instrumentation for studying biomolecular interactions and properties. Surface Plasmon Resonance (SPR), Isothermal Titration Calometry (ITC), and Microscale Thermophoresis (MST) are state-of-the-art techniques to analyse interaction between proteins, DNA, RNA, small molecules and drug compounds. Circular Dichroism Spectroscopy (CD) and Multi Angle Light Scattering (MALS) can be applied to investigate structural properties of proteins and their changes in response to biomolecular interactions.
Devices, services and opportunities for cooperation
Circular dichroism spectrophotometer (CD); Jasco J-815 (Microbiology)
Brüser, T. (Head)
Institute of MicrobiologyResearch infrastructure/Equipment: Research Instrumentation
E-Mail(s): denise.mehnerifmb.uni-hannover.de
URL(s): https://go.lu-h.de/biomolecular-interactions, https://go.lu-h.de/dna-rna-proteins
Differential scanning calorimeter (DSC); TA-Instruments, Nano DSC (Microbiology)
Brüser, T. (Head)
Institute of MicrobiologyResearch infrastructure/Equipment: Research Instrumentation
E-Mail(s): denise.mehnerifmb.uni-hannover.de
URL(s): https://go.lu-h.de/biomolecular-interactions, https://go.lu-h.de/dna-rna-proteins
FPLC + MALS; Akta Pure + Wyatt Technologies miniDAWN SEC-MALS + Optilab T-rEX refractometer
Cox, R. J. (Head)
Centre of Biomolecular Drug Research (BMWZ)Research infrastructure/Equipment: Research Instrumentation
Contact person(s) for booking: Russell John Cox
E-Mail(s): equipmentbmwz.uni-hannover.de
URL(s): https://go.lu-h.de/biomolecular-interactions, https://go.lu-h.de/dna-rna-proteins
Free Flow Electrophoresis System (FFE)
Braun, H.-P. (Head)
Institute of Plant GeneticsResearch infrastructure/Equipment: Research Instrumentation
Contact person(s) for booking: Holger Eubel
E-Mail(s): heubelgenetik.uni-hannover.de
URL(s): https://go.lu-h.de/cell-sorting-analytics, https://go.lu-h.de/biomolecular-interactions, https://go.lu-h.de/dna-rna-proteins
Isothermal Titration Calorimeter (ITC); VP-ITC, MicroCal/ GE-Health Care (Microbiology)
Brüser, T. (Head)
Institute of MicrobiologyResearch infrastructure/Equipment: Research Instrumentation
E-Mail(s): denise.mehnerifmb.uni-hannover.de
Microscale Thermophoresis (MST); Monolith NT.115; Nanotemper
Kara, S. (Head)
Institute of Technical ChemistryResearch infrastructure/Equipment: Research Instrumentation
Contact person(s) for booking: Frank Stahl
E-Mail(s): stahliftc.uni-hannover.de
Multi Angle Light Scattering (MALS); Wyatt miniDAWN TREOS (Microbiology)
Brüser, T. (Head)
Institute of MicrobiologyResearch infrastructure/Equipment: Research Instrumentation
E-Mail(s): denise.mehnerifmb.uni-hannover.de
URL(s): https://go.lu-h.de/biomolecular-interactions, https://go.lu-h.de/dna-rna-proteins
Surface Plasmon Resonance (SPR) biosensor; Reichert 4SPR (Microbiology)
Brüser, T. (Head)
Institute of MicrobiologyResearch infrastructure/Equipment: Major Research Instrumentation
E-Mail(s): denise.mehnerifmb.uni-hannover.de
